Drosophila courtship song rhythms remain data
نویسندگان
چکیده
Authors: 2 David L. Stern, Jan Clemens, Philip Coen, Adam J. Calhoun, John B. Hogenesch, Ben 3 Arthur, and Mala Murthy 4 5 Affiliations: 6 1 Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA 7 2 Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA 8 3 Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA 9 4 University College London, Gower St, Bloomsbury, London WC1E 6BT, UK 10 5 Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229 11 12 13 14 Correspondence: [email protected] 15
منابع مشابه
Experimental and statistical reevaluation provides no evidence for Drosophila courtship song rhythms.
From 1980 to 1992, a series of influential papers reported on the discovery, genetics, and evolution of a periodic cycling of the interval between Drosophila male courtship song pulses. The molecular mechanisms underlying this periodicity were never described. To reinitiate investigation of this phenomenon, we previously performed automated segmentation of songs but failed to detect the propose...
متن کاملFailure to reproduce period-dependent song cycles in Drosophila is due to poor automated pulse-detection and low-intensity courtship.
Stern has criticized a body of work from several groups that have independently studied the so-called "Kyriacou and Hall" courtship song rhythms of male Drosophila melanogaster, claiming that these ultradian ∼60-s cycles in the interpulse interval (IPI) are statistical artifacts that are not modulated by mutations at the period (per) locus [Stern DL (2014) BMC Biol 12:38]. We have scrutinized S...
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Courtship song in Drosophila is produced by the male's wing vibration and consists of pulses of tone produced at intervals of approximately 34 msec in D. melanogaster and 48 msec in D. simulans. We have observed that the intervals between these pulses are not constant but fluctuate rhythmically with periods of approximately 1 min in D. melanogaster and 0.5 min in D. simulans. In D. melanogaster...
متن کاملP-element transformation with period locus DNA restores rhythmicity to mutant, arrhythmic Drosophila melanogaster.
Mutations at the period (per) locus of Drosophila melanogaster disrupt several biological rhythms. Molecular cloning of DNA sequences encompassing the per+ locus has allowed germ-line transformation experiments to be carried out. Certain subsegments of the per region, transduced into the genome of arrhythmic pero flies, restore rhythmicity in circadian locomotor behavior and the male's courtshi...
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The 5-HT(7) receptor remains one of the less well characterized serotonin receptors. Although it has been demonstrated to be involved in the regulation of mood, sleep, and circadian rhythms, as well as relaxation of vascular smooth muscles in mammals, the precise mechanisms underlying these functions remain largely unknown. The fruit fly, Drosophila melanogaster, is an attractive model organism...
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تاریخ انتشار 2017